Recently, researchers in Lei Bo’s team from the Frontier Institute of Science and Technology of XJTU developed an elastomeric, photoluminescent, and antibacterial hybrid polypeptide-based nanofibrous matrix as wound dressings. The matrix showed a biomimetic elastomeric behavior, and robust antibacterial activity. It can efficiently prevent bacterial-derived infection and significantly enhance complete skin-thickness wound healing and skin regeneration in mice. This work might provide a new concept in designing medical materials with high bioactivity for regenerative medicine.
The research result was published in ACS Nano (IF=13.709), an international authoritative journal under the title Biomimetic Elastomeric Polypeptide-Based Nanofibrous Matrix for Overcoming Multidrug-Resistant Bacteria and Enhancing Full-Thickness Wound Healing/Skin Regeneration. The XJTU Frontier Institute of Scienceand Technology is the institutional affiliation of the first author and the corresponding author.