Regulation mechanism of the 1p36.12 locus unveiled

2018-07-11  []


    

Recently, Professor Yang Tielin from the School of Life Science and Technology of XJTU published an article revealing the regulation mechanism of the 1p36.12 locus in non-coding variants through the studies of the disease osteoporosis.        

   

The article was published on American Journal of Human Genetics (AJHG, Impact Factor 10.25) with the title of  “An Osteoporosis Risk SNP at1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expressionvia Long- Range Loop Formation."        

   

Link to the article: https://www.cell.com/ajhg/fulltext/S0002-9297(18)30090-9

   


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